产品货号：
Z37842
中文名称：
Glucocorticoid receptor/NR3C1抗体
英文名称：
Anti-Glucocorticoid receptor/NR3C1 Antibody (Clone#2153CT307.32.80)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Glucocorticoid receptor/NR3C1 Antibody (Clone#2153CT307.32.80) |
| 指标别名 | GCCR;GCR;Glucocorticoid receptor;GR;GRL;NR3C1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB |
| 基因名称 | NR3C1 |
| 克隆号 | 2153CT307.32.80 |
| 抗体来源 | Mouse |
| 免疫原 | This antibody is generated from a mouse immunized with a recombinant protein from human. |
| 计算分子量 | 86kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Receptor for glucocorticoids (GC) (PubMed:27120390).Has a dual mode of action:as a transcription factor that binds to glucocorticoid response elements (GRE),both for nuclear and mitochondrial DNA,and as a modulator of other transcription factors.Affects inflammatory responses,cellular proliferation and differentiation in target tissues.Involved in chromatin remodeling (PubMed:9590696).Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A,leading to RNA decay (PubMed:25775514).Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth (By similarity). |
| Uniprot ID | P04150 |
相关搜索：Glucocorticoid receptor/NR3C1抗体，Glucocorticoid receptor抗体，NR3C1单抗